The term "City routes" in the current TUIfly flight schedule refers to all domestic German routes and to the destinations stated below:
| Destinations in Winter 2009/2010 | Destinations in Summer 2010 | |
| Flights from 25.10.09 – 27.03.10 from/to: | Flights from 28.03.10 from/to: | |
| Bari | Algiers | |
| Brindisi | Bari | |
| Cagliari | Brindisi | |
| Catania | Cagliari | |
| Graz | Calvi | |
| Innsbruck | Catania | |
| Klagenfurt | Dubrovnik | |
| Milan | Graz | |
| Nador | Innsbruck | |
| Naples | Klagenfurt | |
| Olbia | Malaga | |
| Palermo | Milan | |
| Porto | Nador | |
| Rijeka | Naples | |
| Rome | Olbia | |
| Salzburg | Palermo | |
| Thessaloniki | Pisa | |
| Tangiers | Rijeka | |
| Tunis | Porto | |
| Valencia | Rijeka | |
| Venice | Rimini | |
| Vienna | Rome | |
| Salzburg | ||
| Thessaloniki | ||
| Tangiers | ||
| Tunis | ||
| Valenica | ||
| Venice | ||
| Vienna |